| Bioactivity | [Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist[1][2]. |
| Invitro | [Nle13]-Motilin (0.1-30 nM, 15 min) increases the amplitude of electrically-evoked, neuronally-mediated contractions in the isolated gastric antrum[1].[Nle13]-Motilin (0.3 μM, 10 min) induces a moderate increase in spontaneous contractility in the stomach[2]. |
| Name | [Nle13]-Motilin |
| CAS | 55524-56-6 |
| Shortening | FVPIFTYGELQR-{Nle}-QEKERNKGQ |
| Formula | C121H190N34O35 |
| Molar Mass | 2681.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dass NB, et al. The rabbit motilin receptor: molecular characterisation and pharmacology. Br J Pharmacol. 2003 Nov;140(5):948-54. [2]. Venkova K, et al. Effect of TZP-201, a novel motilin receptor antagonist, in the colon of the musk shrew (Suncus murinus). J Pharm Pharmacol. 2009 Mar;61(3):367-73. |